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America

April 28, 2005

Bacteria could lead to biological computers

SCIENTISTS have programmed bacteria to “talk” to one another and produce colour-coded patterns in a study that paves the way for “biological computers” and new ways of detecting biological and chemical weapons.

The experiment in the United States shows that living cells can be harnessed to perform specialist tasks and could be exploited for medical and civil defence technologies.

Bacteria or other cells could be linked into networks that would pick up traces of anthrax or chemical weapons, or to build biological machines that repair tissues or organs in the body, researchers said.

Ron Weiss led the study at the California Institute of Technology. In the research, Dr Weiss’s team took colonies of E. coli bacteria and genetically engineered them to produce green or red fluorescent proteins in response to chemical signals released by other bacteria. Details are published today in the journal Nature.

The modified bacteria formed a “bull’s-eye” pattern in response to the position of sender cells that could be used to show the presence of chemical agents, Dr Weiss said.

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